Alert

Scleroderma

Scleroderma is an uncommon disease in which parts of the skin, joints, and blood vessels break down and are replaced by fibrous tissue. Organ damage may also occur, which can lead to lung, kidney, or heart failure and other life-threatening conditions.

Symptoms of scleroderma include thickening of the skin, joint pain and stiffness, problems swallowing, and cold fingertips that may turn white or blue (Raynaud's phenomenon). More serious symptoms may occur as the disease progresses and affects major organs.

Scleroderma is most common in middle-aged women. Its cause is unknown. But it may occur from an autoimmune disease, which is when the body's defense system (immune system) attacks its own tissues. There is no cure. But treatment can help relieve symptoms and prevent complications.

Symptom Checker

Feeling under the weather?

Use our interactive symptom checker to evaluate your symptoms and determine appropriate action or treatment.

Interactive Tools

Get started learning more about your health!

Our Interactive Tools can help you make smart decisions for a healthier life. You'll find personal calculators and tools for health and fitness, lifestyle checkups, and pregnancy.

Top