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hydrochlorothiazide and lisinopril

Pronunciation: HYE droe KLOR oh THYE a zide and lye SIN oh pril

Brand: Zestoretic

Hydrochlorothiazide-Lisinopril

slide 1 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-10 mg, round, blue, imprinted with WW 62

Image of Hydrochlorothiazide-Lisinopril
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Hydrochlorothiazide-Lisinopril

slide 2 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-20 mg, round, yellow, imprinted with WW 63

Image of Hydrochlorothiazide-Lisinopril
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Hydrochlorothiazide-Lisinopril

slide 3 of 44, Hydrochlorothiazide-Lisinopril,

25 mg-20 mg, round, red, imprinted with WW 64

Image of Hydrochlorothiazide-Lisinopril
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Hydrochlorothiazide-Lisinopril

slide 4 of 44, Hydrochlorothiazide-Lisinopril,

25 mg-20 mg, round, pink, imprinted with 20/25, Logo 5032

Image of Hydrochlorothiazide-Lisinopril
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Hydrochlorothiazide-Lisinopril

slide 5 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-10 mg, round, blue, imprinted with 10/12.5, Logo 5033

Image of Hydrochlorothiazide-Lisinopril
slide 5 of 44
    

Hydrochlorothiazide-Lisinopril

slide 6 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-20 mg, round, yellow, imprinted with 20/12.5, Logo 5034

Image of Hydrochlorothiazide-Lisinopril
slide 6 of 44
    

Hydrochlorothiazide-Lisinopril

slide 7 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-20 mg, round, white, imprinted with E 152

Image of Hydrochlorothiazide-Lisinopril
slide 7 of 44
    

Hydrochlorothiazide-Lisinopril

slide 8 of 44, Hydrochlorothiazide-Lisinopril,

25 mg-20 mg, round, pink, imprinted with E 173

Image of Hydrochlorothiazide-Lisinopril
slide 8 of 44
    

Hydrochlorothiazide-Lisinopril

slide 9 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-10 mg, round, pink, imprinted with E 71

Image of Hydrochlorothiazide-Lisinopril
slide 9 of 44
    

Hydrochlorothiazide-Lisinopril

slide 10 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-10 mg, round, white, imprinted with M, LH1

Image of Hydrochlorothiazide-Lisinopril
slide 10 of 44
    

Hydrochlorothiazide-Lisinopril

slide 11 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-20 mg, round, yellow, imprinted with M, LH2

Image of Hydrochlorothiazide-Lisinopril
slide 11 of 44
    

Hydrochlorothiazide-Lisinopril

slide 12 of 44, Hydrochlorothiazide-Lisinopril,

25 mg-20 mg, round, green, imprinted with M, LH3

Image of Hydrochlorothiazide-Lisinopril
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Hydrochlorothiazide-Lisinopril

slide 13 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-10 mg, round, pink, imprinted with WATSON 860

Image of Hydrochlorothiazide-Lisinopril
slide 13 of 44
    

Hydrochlorothiazide-Lisinopril

slide 14 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-20 mg, round, blue, imprinted with WATSON 861

Image of Hydrochlorothiazide-Lisinopril
slide 14 of 44
    

Hydrochlorothiazide-Lisinopril

slide 15 of 44, Hydrochlorothiazide-Lisinopril,

25 mg-20 mg, round, pink, imprinted with WATSON 862

Image of Hydrochlorothiazide-Lisinopril
slide 15 of 44
    

Hydrochlorothiazide-Lisinopril

slide 16 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-10 mg, round, pink, imprinted with E 71

Image of Hydrochlorothiazide-Lisinopril
slide 16 of 44
    

Hydrochlorothiazide-Lisinopril

slide 17 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-20 mg, round, white, imprinted with E 152

Image of Hydrochlorothiazide-Lisinopril
slide 17 of 44
    

Hydrochlorothiazide-Lisinopril

slide 18 of 44, Hydrochlorothiazide-Lisinopril,

25 mg-20 mg, round, pink, imprinted with E 173

Image of Hydrochlorothiazide-Lisinopril
slide 18 of 44
    

Hydrochlorothiazide-Lisinopril

slide 19 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-10 mg, round, white, imprinted with LH1, M

Image of Hydrochlorothiazide-Lisinopril
slide 19 of 44
    

Hydrochlorothiazide-Lisinopril

slide 20 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-20 mg, round, yellow, imprinted with LH2, M

Image of Hydrochlorothiazide-Lisinopril
slide 20 of 44
    

Hydrochlorothiazide-Lisinopril

slide 21 of 44, Hydrochlorothiazide-Lisinopril,

25 mg-20 mg, round, green, imprinted with LH3, M

Image of Hydrochlorothiazide-Lisinopril
slide 21 of 44
    

Hydrochlorothiazide-Lisinopril

slide 22 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-20 mg, round, yellow, imprinted with RX 537

Image of Hydrochlorothiazide-Lisinopril
slide 22 of 44
    

Hydrochlorothiazide-Lisinopril

slide 23 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-10 mg, round, pink, imprinted with A, 26

Image of Hydrochlorothiazide-Lisinopril
slide 23 of 44
    

Hydrochlorothiazide-Lisinopril

slide 24 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-20 mg, round, yellow, imprinted with A, 28

Image of Hydrochlorothiazide-Lisinopril
slide 24 of 44
    

Hydrochlorothiazide-Lisinopril

slide 25 of 44, Hydrochlorothiazide-Lisinopril,

25 mg-20 mg, round, pink, imprinted with A, 27

Image of Hydrochlorothiazide-Lisinopril
slide 25 of 44
    

Hydrochlorothiazide-Lisinopril

slide 26 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-10 mg, hexagonal, blue, imprinted with LL, B01

Image of Hydrochlorothiazide-Lisinopril
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Hydrochlorothiazide-Lisinopril

slide 27 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-20 mg, round, yellow, imprinted with LL, B02

Image of Hydrochlorothiazide-Lisinopril
slide 27 of 44
    

Hydrochlorothiazide-Lisinopril

slide 28 of 44, Hydrochlorothiazide-Lisinopril,

25 mg-20 mg, round, orange, imprinted with LL, B03

Image of Hydrochlorothiazide-Lisinopril
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Hydrochlorothiazide-Lisinopril

slide 29 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-10 mg, round, blue, imprinted with RX 536

Image of Hydrochlorothiazide-Lisinopril
slide 29 of 44
    

Hydrochlorothiazide-Lisinopril

slide 30 of 44, Hydrochlorothiazide-Lisinopril,

25 mg-20 mg, round, peach, imprinted with GP 123

Image of Hydrochlorothiazide-Lisinopril
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Hydrochlorothiazide-Lisinopril

slide 31 of 44, Hydrochlorothiazide-Lisinopril,

25 mg-20 mg, round, peach, imprinted with RX 538

Image of Hydrochlorothiazide-Lisinopril
slide 31 of 44
    

Hydrochlorothiazide-Lisinopril

slide 32 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-10 mg, round, peach, imprinted with 93, 1035

Image of Hydrochlorothiazide-Lisinopril
slide 32 of 44
    

Hydrochlorothiazide-Lisinopril

slide 33 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-20 mg, round, white, imprinted with 93, 1036

Image of Hydrochlorothiazide-Lisinopril
slide 33 of 44
    

Hydrochlorothiazide-Lisinopril

slide 34 of 44, Hydrochlorothiazide-Lisinopril,

25 mg-20 mg, round, pink, imprinted with 20/25, Logo 5032

Image of Hydrochlorothiazide-Lisinopril
slide 34 of 44
    

Hydrochlorothiazide-Lisinopril

slide 35 of 44, Hydrochlorothiazide-Lisinopril,

25 mg-20 mg, round, pink, imprinted with 93, 1037

Image of Hydrochlorothiazide-Lisinopril
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Hydrochlorothiazide-Lisinopril

slide 36 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-10 mg, oval, pink, imprinted with 10 12.5, APO

Image of Hydrochlorothiazide-Lisinopril
slide 36 of 44
    

Hydrochlorothiazide-Lisinopril

slide 37 of 44, Hydrochlorothiazide-Lisinopril,

12.5 mg-20 mg, oval, white, imprinted with 20 12.5, APO

Image of Hydrochlorothiazide-Lisinopril
slide 37 of 44
    

Hydrochlorothiazide-Lisinopril

slide 38 of 44, Hydrochlorothiazide-Lisinopril,

25 mg-20 mg, oval, pink, imprinted with 20 25, APO

Image of Hydrochlorothiazide-Lisinopril
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Prinzide

slide 39 of 44, Prinzide,

12.5 mg-10 mg, hexagonal, white, imprinted with PRINZIDE, MSD 145

Image of Prinzide
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Prinzide

slide 40 of 44, Prinzide,

12.5 mg-20 mg, round, yellow, imprinted with MSD 140, PRINZIDE

Image of Prinzide
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Prinzide

slide 41 of 44, Prinzide,

25 mg-20 mg, round, yellow, imprinted with PRINZIDE, MSD 142

Image of Prinzide
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Zestoretic

slide 42 of 44, Zestoretic,

12.5 mg-10 mg, round, peach, imprinted with ZESTORETIC, 141

Image of Zestoretic
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Zestoretic

slide 43 of 44, Zestoretic,

12.5 mg-20 mg, round, white, imprinted with ZESTORETIC, 142

Image of Zestoretic
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Zestoretic

slide 44 of 44, Zestoretic,

25 mg-20 mg, round, peach, imprinted with ZESTORETIC, 145

Image of Zestoretic
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What is the most important information I should know about hydrochlorothiazide and lisinopril?

Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away.

You should not use this medicine if you have ever had angioedema, if you are unable to urinate, or if you are allergic to sulfa drugs or to any ACE inhibitor. Do not take hydrochlorothiazide and lisinopril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).

If you have diabetes, do not use hydrochlorothiazide and lisinopril together with any medication that contains aliskiren (a blood pressure medicine).

What is hydrochlorothiazide and lisinopril?

Hydrochlorothiazide is a thiazide diuretic (water pill). Lisinopril is in an ACE inhibitor (ACE stands for angiotensin converting enzyme).

Hydrochlorothiazide and lisinopril is a combination medicine used to treat hypertension (high blood pressure). Lowering blood pressure may lower your risk of a stroke or heart attack.

Hydrochlorothiazide and lisinopril may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking hydrochlorothiazide and lisinopril?

You should not use this medicine if you are allergic to hydrochlorothiazide or lisinopril, or if:

  • you have hereditary angioedema;
  • you are unable to urinate;
  • you recently took a heart medicine called sacubitril;
  • you have an allergy to sulfa drugs; or
  • you have ever had a severe allergic reaction to any ACE inhibitor (benazepril, captopril, enalapril, fosinopril, moexipril, perindopril, quinapril, ramipril, trandolapril).

Do not take hydrochlorothiazide and lisinopril within 36 hours before or after taking medicine that contains sacubitril (such as Entresto).

If you have diabetes, do not use hydrochlorothiazide and lisinopril together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking hydrochlorothiazide and lisinopril with aliskiren if you have kidney disease.

Tell your doctor if you have ever had:

  • kidney disease (or if you are on dialysis);
  • cirrhosis or other liver disease;
  • glaucoma;
  • heart disease or congestive heart failure;
  • asthma or allergies;
  • gout;
  • lupus;
  • an allergy to sulfa drugs or penicillin; or
  • if you are on a low-salt diet.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Lisinopril can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

You should not breastfeed while using hydrochlorothiazide and lisinopril.

Hydrochlorothiazide and lisinopril is not approved for use by anyone younger than 18 years old.

How should I take hydrochlorothiazide and lisinopril?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medicine. This can lead to very low blood pressure, electrolyte disorders, or kidney failure.

Your blood pressure will need to be checked often, and you may need occasional blood tests.

If you need surgery, tell your surgeon you currently use this medicine.

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking hydrochlorothiazide and lisinopril?

Drinking alcohol can further lower your blood pressure and may increase certain side effects of this medicine.

Do not use potassium supplements or salt substitutes while you are taking this medicine, unless your doctor has told you to.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.

What are the possible side effects of hydrochlorothiazide and lisinopril?

Get emergency medical help if you have signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • eye pain, vision problems;
  • little or no urination;
  • weakness, drowsiness, or feeling restless;
  • fever, chills, sore throat, mouth sores, trouble swallowing;
  • jaundice (yellowing of the skin or eyes);
  • high potassium --nausea, tingly feeling, chest pain, irregular heartbeats, loss of movement;
  • low potassium --leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling; or
  • low sodium --headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady.

Common side effects may include:

  • cough;
  • headache;
  • dizziness; or
  • tired feeling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect hydrochlorothiazide and lisinopril?

Tell your doctor about all your other medicines, especially:

  • any other blood pressure medication;
  • lithium;
  • everolimus, sirolimus, temsirolimus; or
  • NSAIDs (nonsteroidal anti-inflammatory drugs) --aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

This list is not complete. Other drugs may affect hydrochlorothiazide and lisinopril, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your pharmacist can provide more information about hydrochlorothiazide and lisinopril.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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